节点文献
茯苓素与小鼠腹腔细胞膜蛋白及牛血清蛋白的结合作用
Effects of Poriatin on Mouse Peritoneal Macrophage Membrane and Calf Serum Proteins in Vitro
【摘要】 <正> 中药茯苓(Poria)中的小分子提取物茯苓素(Poriatin)在体外能抑制小鼠白血病L1210细胞的DNA合成,其原发作用点在细胞膜上。本实验进一步研究茯苓素在体外对小鼠腹腔细胞膜的作用。
【Abstract】 This experiment demonstrated that poriatin was able to combine with calf serum proteins tightly and irreversibly, and destruct plasma membrane when serum was absent or poriatin was used in a very high concentration. The results suggested that poriatin might conjugate to proteins on plasma membrane, and then change the activities of ectoenzymes, inhibit the function of membrane and even cause damage of the cells.
- 【文献出处】 中国医学科学院学报 ,Acta Academiae Medicinae Sinicae , 编辑部邮箱 ,1988年04期
- 【被引频次】20
- 【下载频次】82