【摘要】 本文用等电聚焦电泳技术调查了258名广东地区人群血清转铁蛋白表型,并根据所得资料计算了这一多态性系统的法医学非父排除机率及个体识别率,对血痕Tf的可测性进行了初步探讨,此外,本实验还摸索了国产试剂用于检测这一多态系统的电泳条件。更多还原

【Abstract】 The distribution of transferrin phenotypes in the population of Guangdong, China, was investigated by isoelectic focusing on polyacrylamide gel. In our samples(n = 258), the frequencies of five phenotypes were as follows: TfC1C1 = 50.20%, TfC2C1 = 31.39%, TfC2C2 = 5.43 % TfC1D=5.43% and TfC1B= 1.55%, The allele frequencies were calculted: TfC1 = 0.7539, Tfc2= 0.2112, TfD= 0.0271 and TfB= 0.0078’ The observed expected phenotypes provided a good fit to Hardy-weinberg equelibrum. The analysis of 6 mother-child pairs was in agreement with Mendelian inheritance. The phenotypes of TfCiCl, TfC2C2 and TfC2C2 were compared to those found in other populations.Based on the data, the probabibity of excluding paternity and discriminating powers(DP) were 0.1803 and 0.5795, respectively. The Tf phenotypes of bloodstains can be possibly typed at 3C for up to four weeks, 11° -17℃ for up to five days and 37℃ for up to two days.更多还原