【摘要】 本文通过衰减全反射红外光谱,透射电镜,扫描电镜,固-液接触角等分析测试研究了聚氨酯-聚硅氧烷共聚物的表面微观形态和表面性质,同时使用Lee White凝血时间测定和血小板扩张试验评价了聚合物的抗凝血性。实验结果表明,聚氨酯-聚硅氧烷共聚物具有硬段微区(30～60(?))-聚醚软段相的微相分离结构以及聚二甲基硅氧烷-聚氨酯基体的微相分离结构,同时聚氨酯-聚硅氧烷共聚物的临界表面张力在24～27达因/厘米,共聚物的抗凝血性既优于聚氨酯。又优于聚硅氧烷。更多还原

【Abstract】 <ABSTRACT>Surface microstructure of polyurethane-polysiloxane copolymer was stud-ied by means of attenuated total reflection-infrared spectrometry,transmis-sion electron microscopy,scanning electron microscopy and contact angle measu-rement,and antithrombogenicity of polymers evaluated using whole blood clot-ting time (Lee White ) and platelet adliension and deformation tests. Rxperi-mental results indicated that polyurethane-polysiloxane copolymers have micro-phase separation morphology of urethane hard segment domains (30-60A)with polyether soft segment matrix and polydimethylsiloxane domains (1-10μ)with polyurethane matrix. Because of hydrophobicity of polysiloxane, criti-cal surface tentiou of these copolymers was decreased to 24-27 dynes/cm.These copolymers have more excellent antithrombogenicity than simple polyurethane and polysiloxane.更多还原