【摘要】 精液免疫抑制物质可使妇女免罹过敏反应或不育,也可减少男性发生自身免疫反应。深入研究不仅有助于阐明带父体基因的受精卵为何不被排斥等正常生育机理,而且也可为寻找不育病因奠定基础.本文报道了人类精浆及其提取物在体内.外对NK活性的抑制效应;同时发现,同种小鼠精子经静脉注射或直肠灌注后也有抑制NK活性;以模拟同性恋活动方式,即肛门灌注人类精浆及其提取物或小鼠精子,发现抑制效应更为显著.更多还原

【Abstract】 In this paper,immunosuppression ofNK activity induced by(1)Human se-minal Plasma(HSP)and its Fraction-1 on sephadex G-100 in vitro;(2)in-travenous injection of HSP,Fraction-1 or mice sperm and(3)uptake of HSP,Fraction-1 or,mice sperm via rectalroute were studied.It has been pro-ved by our experiment that HSP,Fraction-1 and mice sperm possesspotent immunosuppressive effect interm of NK activity inhibition.Ascompared with intravenous injection,the immunosuppression induced byrectal exposure of HSP,Fraction-1or mice sperm is much stronger更多还原