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老年冠心病患者血清载脂蛋白及脂蛋白组分水平的观察

Serum Apolipoproteins and Lipoprotein Fraction Levels of the Elderly Patients with Coronary Heart Disease

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【作者】 李宝山; 白广林; 刘金; 左云飞; 唐煦; 康德伸; 王瑞琨; 张克贤; 孙景勤; 李景林; 赵博光;

【Author】 Li Baoshan et al Department of Biochemistry, Inner Mongolia Medical College, Inner Mongolia Region

【机构】 内蒙古蒙医学院生化教研室; 通辽市第一人民医院; 通辽市第一人民医院;

【摘要】 本文报道207例健康老年人和71例冠心病老年人血清载脂蛋白及脂蛋白组分含量的变化。结果显示冠心病患者的TC、TG、LDL-C、ApoB.、LDL-C/HDL、ApoA-I/HDL-C显著高于健康老年人。单因素相关分析显示冠心病的HDL-C与LDL-C、TG呈明显的负相关,而与HDL-PL是正相关。高胆固醇血症的冠心病患者HDL-C、ApoA-I显著低于健康老年人,而TG相反。

【Abstract】 The levels of serum apolipoproteins and lipoprotein fractions were determinedin 207 healthy elderly subjects and 71 elderly patients with coronary heart disease(CHD). The results showed that the parameters of TC, TG, LDL-C ApoB, LDL-C/HDL-C,and ApoA-I/HDL-C of the patients with CHD were much higher than heal-thy elderly subjects, but HDL-C/TC, HDL-PL/TC were much lower. The analyses of linear correlation indicated that the parameters of HDL-Cshowed significantly negative correlated to the LDL-C, TC of the patients withCHD, But HDL-PL positively correlated. The parameters of HDL-C,ApoA-I in the CHD patients with hypercholesterola-emia were much lower as compared to the healthy elderly subjects, but TG washigher.

【关键词】 冠心病; 载脂蛋白; 脂蛋白;
【Key words】 Coronary heart disease; Apolipoprotein; lipoprotein;
  • 【被引频次】5
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