【摘要】 100例临床诊断晚期血吸虫病(晚血)患者的临床资料和肝活组织病理检查、乙型肝炎病毒(HBV)标志检查结果对照分析,发现100例中病理诊断为单纯血吸虫病仅12例,血吸虫病伴有乙型肝炎(乙肝)53例,单纯乙肝35例。血清HBV标志阳性率为67.1％,肝活组织地依红染色HBsAg阳性38％,提示临床诊断晚血的绝大多数患者伴有HBV感染。更多还原

【Abstract】 The pathological features of liver biopsy and HBV markers (ihcluding serum HBsAg, anti-HBc, anti-HBs and Orcein stain of HBsAg) were studied in 100 clinically diagnosed advanced schistosomiasis cases and correlative analysis was made with clinical data.The results showed that out of 100 cases twelve cases were pathologically diagnosed as simple schistosomiasis, 53 cases as schistosomiasis accompanied with chronic hepatitis B, and 35 as simple chronic hepatitis B.Histological Identification of the 53 cases of schistosomiasis accompanied with chronic hepatitis was classified as light hepatitis in 15, chronic prolonged hepatitis in 14, chronic active hepatitis in 5, and chronic active hepatitis with post-hepatic cirxhosis in 19 (35.8%). indicating that the liver damage in majority of clinically diagnosed schistosomiasis was due to HBV. A positive rate of HBV markers as high as 67.1% in serum and 38% of positive Orcein stain of HBsAg in liver biopsy are supportive to this argument.The possible relationship of HBV infection in advanced schistosomiasis patients to blood transfusion and the possible immune suppression mechanism are discussed.更多还原