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安宁和泛酸钙的氨气敏电极测定法

DETERMINATION OF MEPROBAMATE AND CALCIUM PANTOTHENATE WITH AMMONIA GAS-SENSING ELECTRODE

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【作者】 李崇俊仲跻德孙嘉奎张剑飞夏明奎高锡范

【Author】 LI Chong-Jun ZHONG Ji-De SUN Jia-Kui ZHANG Jian-Fei XIA Ming-Kui GAO Xi-Fan (Shengyang Callege of Pharmacy;Zhumadian Institute for Drug Control,Henan)

【机构】 沈阳药学院河南驻马店药检所沈阳药学院 1986年毕业生1986年毕业生

【摘要】 安宁及其制剂和泛酸钙,经降解成相应的铵盐,两者于浓碱存在下均逸出 NH3,可用氨气敏电极测定。在1×10-4~1×10-2mol/L 浓度范围内,校正曲线呈线性,所测得结果与凯氏定氮法基本一致。

【Abstract】 Meprobamate and its preparations as well as calcium pantothe-nate were decomposed to form the corresponding ammonium salts.The ammoniaevolved at pH>11 from the above solutions could be determined directly usingan ammonium gas-sensing electrode.The calibration curves showed the linearityin the range of 1×10-4~1×10-2 mol/L.The results obtained were comparable tothose by Kjeldahl method.

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