【摘要】 久效磷是一种高毒性农药,易经皮肤吸收。本文采用人和幼猪离体皮肤实验模型及¹⁴C-久效磷标记化合物,研究久效磷的经皮肤渗透作用。结果表明,久效磷可经人体无伤皮肤渗透,其渗透量和渗透速度与皮肤接触农药的时间有关。久效磷的经皮渗透作用,人体不同部位皮肤有明显差异,其中以面颊皮肤最易渗透。及时清洗皮肤污染对防止久效磷大量经皮吸收具有重要意义。更多还原

【Abstract】 The monocrotophos is a highlytoxic insecticide.It is easily absorbedthrough the skin.A study was carriedout on the percutaneous permeabilityof monocrotophos in human boby andpig skin models in vitro.The resultsshowed that the monocrotophos canpenetrate through intact skin.Theamount and rate of penetrationthrough the skin was related to theduration of exposure to monocrotophos.The percutaneous permeability wasdifferent to different parts of humanskin,being greatest in cheek skin.Itis important that contamination of skinby monocrotophos should be removedas soon as possible in order to pre-vent percutaneous absorption of mo-nocrotophos.更多还原