【摘要】 本文移植了啤酒酵母菌D₇,株对致突变/致癌物质的快速检测方法,并以四种化学物质对D₇株生长期细胞进行了遗传效应观察。其中甲基-硝基-亚硝基胍（MNNG）、甲磺酸乙酯（EMS）在存活细胞总变异率及其他两个终点上均见到剂量效应关系,农药敌克松（Dexon）亦表现出弱阳性,而化学品N.P.C在存活细胞被杀伤到30%时,仍未诱导出明显的效应,可判为阴性结果。更多还原

【Abstract】 A rapid method for mutagenic de-tection with Saccharomyces CerevisiaeD7 was described.Genetic effects of4 chemicals (MNNG,EMS,pesticideDe-xon and NPC （[Na₂PO₄·11H₂O]₄ NaClO）were tested with growing cells of thestrain D7. The mutagenicity of MNNG andEMS was found to be dose-responsivelyrelated with the frequency of total ab-errant of survivors,gene conversion andreverse mutation. Result of the test also showed thatweak mutagenicity appeared with thepesticide Dexon,but compound NPCwas negative.更多还原