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睾丸精原细胞瘤的放射治疗——附119例临床分析
RADIOTHERAPY OF TESTICULAR SEMINOMA——Analysis of 119 cases
【摘要】 <正> 睾丸肿瘤是泌尿系统中常见的恶性肿瘤之一,其中生殖细胞瘤约占所有睾丸肿瘤的95%以上,非生殖细胞瘤占3~5%,生殖细胞瘤有四种基本组织类型:精原细胞瘤、胚胎瘤、畸胎瘤和绒毛膜癌。单纯一种细胞类型占睾丸肿瘤的60%,一种以上细胞类型占40%。
【Abstract】 Testicular seminoma, though prone to lymphatic spread, is very radiosensitive. A high survival rate is expected by orchiectomy plus radiotherapy. 119 patients with testicular seminoma treated by radiotherapy in our institute from Jan. 1971 to Dec. 1982 are reported. All were confirmed by pathology. According to Boden and Maier’s Staging system, 81 (68%) patients were stage Ⅰ, 27 (23%) were stage Ⅱ and 11 (9%) stage Ⅲ. Survival rates were calculated by the life table method, The 5 and 10 year survivals were 98%, 98% for stage Ⅰ, 90%, 45% for stage Ⅱ and 55%, 0 % for stage Ⅲ respectively. The differences between the survivals of stage Ⅰ, Ⅱ and Ⅲ were of statistical significance. Due to the fact that distant metastasis is the chief cause of death, we suppose the advanced lesions might benefit from adjutant chemotherapy. Patients with localized metastases outside the irradiated area could be managed with extended radiation. Postoperative radiotherapy with an optimum dose of about 25-35 Gy/3-4 weeks for testicular seminoma is recommended.
- 【文献出处】 中国放射肿瘤学 ,Chinese Journal of Radiation Oncology , 编辑部邮箱 ,1988年03期
- 【被引频次】2
- 【下载频次】21