【摘要】 <正> 鼻咽癌是我国最常见的头颈部恶性肿瘤之一,至今仍有不少关于鼻咽癌生物学特性的问题尚未清楚。 将人体恶性肿瘤组织移植到先天性无胸腺裸小鼠来形成裸鼠人体肿瘤已成为当前癌症研究工作的重要方法之一;它的主要基础是裸鼠人体肿瘤具有其原发人体肿瘤相更多还原

【Abstract】 Nasopharyngeal carcinoma was successfully transplanted into nude mice, and has been maintained through 20 passages during the recent four years, With flow cytometer (FCM), the cellular DNA content of the primary human cancer and the xenograft in various passages were assayed. The histograms showed that the human cancer and the xenografts were diploid. It was found that the DNA index and the proliferation index remained constant in both the primary and transplanted tumor. The distribution of various phase cells in the cell cycle were similar to those of the primary tumor. The stability of the DNA index indicates that no significant changes in the chromosome has occurred during the past four years. The authors believe that the application of FCM to assay the stability of biological characteristics.更多还原