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重症肝炎治疗的研究

STUDY OF TREATMENT FOR FULMINANT HEPATITIS

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【作者】 董祥家; 关仲英; 张捷; 王兆荃; 霍宏慎; 张曾跃; 孟令先; 乔光彦; 林新; 李彦卿; 金玉珠; 王迎春; 张炎; 赵凤桐; 张振藩; 聂希娣; 张敬铭;

【Author】 Dong Xiangjia, et al (The Third Affiliated Hospital, China Medical University)

【机构】 中国医科大学附属第三医院传染病学教研室; 沈阳市第一传染病院; 沈阳市第二传染病院; 沈阳市第二传染病院;

【摘要】 本文报告经肝脏活体组织检查证实的重症肝炎50例治疗结果。采用一般疗法12例,死亡10例;而采用综合基础疗法的38例,死亡16例,成活22例(57.89%)明显高于对照组,并就综合基本疗法的用药方法和剂量等问题进行了探讨。

【Abstract】 Fatality rate for severe hepatitis (SH) is very high. Because pathogenesis for SH is complieated, synthetical treatment should be taken in order to improve survival rate. In 50 reported cases of SH which were confirmed by liver biopsy, 8 were acute SH, 42 were subacute SH based on pathological grouping. 26 of 50 cases died. The fatality rate was 52%.In 38 cases treated with complex amino acid, peptide thymus, plasma or human albumen and glu-cagon-insulin, 16 died. Fatality rate wae 42.11%, survival rate 57.89%.Liver biopsy was performed in one of 22 cases on the 37th day of onset. The second liver biopsy showed that hepatocytes were hyper plasia and recovered but there was an area of necrosis.Ten of 12 patients with subacute SH recovered to mild or middle chronic active hepatitis. Their fosi of necrosis recovered.Only 2 cases of subacute SH showed changes of severe chronic active hepatitis and early hepatocirrhosis.

【关键词】 重症肝炎; 治疗;
【Key words】 Fulminant hepatitis; Treatment;
【基金】 国家“六五”攻关课题
  • 【文献出处】 中国医科大学学报 ,Journal of China Medical University , 编辑部邮箱 ,1988年03期
  • 【被引频次】5
  • 【下载频次】19
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