【摘要】 1.本文报道了HLA—DR、DQ抗原在沈阳汉族人群中的分布,HLA—DR基因频率为0.8132,尚有空白0.1868,HLA—DQ基因频率为0.7964,尚有空白0.2036。说明沈阳地区汉族人群无论HLA—DR或HLA—DQ均有新的抗原未被发现。2.HLA—DR1明显高于上海、湖北及四川;HLA—DR 3明显低于湖北,略低于上海;HLA—DR 4明显低于湖北,HLA—DR 7明显低于上海,HLA—DRw9明显低于上海、四川。HLA—DQw 3明显低于四川。3.本文首次在中国沈阳汉族人群中检测到HLA—DQw 2、DOwa、TA10。更多还原

【Abstract】 HLA-DR and DQ antigen of 100 unrelated Shenyang citizens of Han nationality were typed and compared with those in Shanghai, Hubei and Sichuan province. The typing method was used by two stage standard complement microcytotoxicity test. HIA-DR and DQ gene frequencies were first examined. The results indicated that DR 0.8132, blank 0.1868; DQ 0.7964, blank 0.2036. It was found that the gene frequencies of HIA-DRI in Shenyang was significantly higher than those in Shanghai, Hubei and Sichuan; while DR3 (and DR4, DR7), DRw9 and DQw3 were significantly lower更多还原