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HPLC测定复方丹参片中丹参三种脂溶性成分的含量
DETERMINATION OF FAT-SOLUBLE COMPONENTS OF SALVIA MILTIORRHIZA IN COMPOUND SALVIA MILTIORRHIZA TABLETS BY HPLC
【摘要】 本文用HPLC法分离了复方丹参片中丹参的三种脂溶性成分隐丹参酮、丹参酮ⅠA、丹参酮ⅡA,并用比较法测定其含量。分析条件是,色谱柱YWGC1810μm(5×150mm),流动相甲醇-水(81.5∶18.5),流速1ml/min,检测波长UV254nm,进样量10μl。三种丹参酮的回收率在99.5~100.9%,变异系数小于1.0%。共测定了七批样品。
【Abstract】 The three active principles of Salvia miltiorrhiza (cryptotanshinone, tanshinone ⅠA and tanshinone ⅡA) in compound Salvia miltiorrhiza tablets were determined by reversed phase HPLC. The liquid chromatograph used was a YSB-DZ chromatograph equipped with YSB-Ⅱ pump, DZ-Ⅰ UV detector (fixed wavelength 254nm), XWT-264 recorder, and a 5×150mm stainless column packed with 10μm YWG C18. The mobile phase was composed of methanol and water (81.5: 18.5). Flow rate was 1.0ml/min. The recoveries of the method were 99.5~100.1% with a coefficients of variation of 1%. Seven batches of compound Salvia miltiorrhiza tablets were determined.
【Key words】 Compound Salvia miltiorrhiza tablets; Cryptotanshinone; Tanshinone Ⅰ_A; Tanshinone Ⅱ_A;
- 【文献出处】 中国药科大学学报 ,Journal of China Pharmaceutical University , 编辑部邮箱 ,1988年03期
- 【被引频次】8
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