【摘要】 选大骨节病活跃重病区患病儿童20名,病区中“正常”儿童20名,非病村儿童20名。取儿童全日尿,用高效薄层色谱法分离尿中多胺,包括腐胺、精脒、精胺和总胺。实验结果看到非病村儿童24小时尿多胺含量分别为腐胺9.8mg,精脒4.0mg,精胺5.7mg,总胺19.5mg;病区“正常”儿童为腐胺12.7mg,精脒4.9mg,精胺6.9mg,总胺24.5mg;病儿为腐胺14.9mg,精脒5.8mg,精胺8.6mg,总胺29.3mg。我们认为尿中多胺增加可能反映大骨节病的增生性改变,并作了扼要讨论。更多还原

【Abstract】 The Paper reports the study on urinary Polyamines of children from the end-emic areas with Kaschin-Beck disease.60 subjects are involved,20 for K.B.diseasepatients from active and severe endemic village,20 for“Normal”children whoshow no changes on X-ray film from the same endemic village and 20 from non-endemic village.urinary Polyamines,included Putrescine,Spermidine and Spermineare separated by HPTLC.The results show that there is slight increse of urinary polyamines on thechildren with K.B.disease,especially for spermine compared with the childrenfrom the nonendemic village.We discussed the significance.更多还原