【摘要】 选用大耳白家兔100只,分成两部分进行实验。第一部分:封闭“百会穴”对家兔针刺降热效应的影响。实验分为针刺——封闭穴位组,针刺——未封闭穴位组;发热对照组(各组动物耳缘静脉注入含EP的上清液引起发热反应)和空白对照组。第二部分:封闭“百会穴”对家兔发热效应的影响。封闭实验组动物穴位,对照组动物穴位不作处理。两组动物耳缘静脉内均注入含EP的上清液引起发热反应。实验结果发现:针刺发热家兔“百会穴”具有明显的降热作用,但针刺封闭发热家兔“百会穴”基本无降热作用。“百会穴”封闭本身对发热没有任何影响。由此,我们推论:针刺“百会穴”的降热作用与该穴位的神经末梢或感受器受作用有密切关系。更多还原

【Abstract】 In 100 rabbits, the febrifugal effect of needling on the endogenous pyrogen fever was studied. These experiments were divided into two parts:Part Ⅰ: Influence of acupoint block on the needling febrifugal effect of rabbit. Eighty rabbits were redivided into 4 groups. Group Ⅰ was with blocking of acupoint "Bai Hui (Hundreds Converge)". In this group, the febrile rabbits were needled after blocking "Bai hui" point with lidocaine (hydrochloride). Group Ⅱ was a group of needling "Bai hui". GroupⅢ was a control group of febrile rabbits. In all the above three groups, febrile effect was induced by intravenous injection of 10ml supernatant containing endogenous pyrogen (Ep). Group Ⅳ was a blank control.Part Ⅱ: Influence of acupoint block on the febrile effect of rabbit. Twenty rabbits were divided into experimental (acupoint block) and control (no block) groups.It was found that needling "Bai hui" point of febrile rabbits would produce marked febrifugal effect, while little febrifugal effect could be observed by needling blocked "Bai hui" point of febrile rabbits. The difference was significant (P<0.01) at the end of 90 minutes. The acupoint block itself, however, produced no effect on the endogenous pyrogen fever. It is thought that the febrifugal effect might be closely associated with free nerve endings or receptors at "Bai hui" point.更多还原