【摘要】 将15只受孕大鼠分为两组,补硒组在孕期和哺乳期饮水中加有2ppm硒,对照组饮普通水,然后测定脑硒含量。补硒组母鼠为0.73±0.11μg/克湿重脑组织,对照组母鼠为0.54±0.09,两组新生鼠分别为0.32±0.02和0.25±0.03,两组生后20日龄的幼鼠分别为0.53±0.04和0.44±0.06。表明口服补充无机硒能够通过胎盘,也能通过胎鼠、幼鼠和成年鼠的血脑屏障。更多还原

【Abstract】 15 rat dams were divided into 2 groups: selenium treated group drank water containing 2 ppm selenium during pregnancy and breast-feeding period, control group drank tap water. The concentration of selenium in brain tissue for dams were 0.73 ±0.11 (Se-treated) and 0.54 ±0.09 ug/g wet tissue (control), for neonates 0.32±0.02 (Se-treated) and 0.25 ± 0.03 (control), and for 20 days old pups 0.53±0.04 (Se-treated) and 0.44±0.06 (control). The results showed that the selenium administered orally could be transfered through placenta or blood-brain barrier of fetus, young pup and adult rat.更多还原