【摘要】 从中药丹参(Salvia miltiorrhiza Bunge)的根中获得5种成分,经鉴定3种为已知物即丹参新酮、铁锈醇及Ro-090680,另2种为新化合物,命名为△~1丹参新酮与△~1-丹参酮Ⅱ_A并观察了它们抑制血小板的聚集活性。更多还原

【Abstract】 Five constituents were isolated from Dan-Shen (Salvia miltiorrhiza). Three of them were identified as miltirone (Ⅱ), ferruginol (Ⅰ) and Ro090680 (Ⅲ). The two others were named △~1-dehydromiltirone and △~1-dehydrotanshinone Ⅱ_A. Ro-090680 has been known as a potent inhibitor of rabbit platelet aggregation in vitro. Related tricyclic diterpenoids such as miltirone and ferruginol were also found to have the same activity.更多还原