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简法合成ω-溴代醇-1
Facile Synthesis of ω-Bromoalkanols
【摘要】 <正> ω-溴代醇-1是合成昆虫信息素、前列腺素等天然产物的重要前体。由α,ω-烷二醇合成ω-溴代醇-1,文献曾有许多报道。最近,Kang 等报道以等摩尔的烷二醇
【Abstract】 A facile process for preparation of ω-bromoalkanols was described.Reflux of equalmolar α,ω-alkanediols and hydromic acid in benzene or toluene yields the ω-bromoalkanolswith a high reaction selectivity of 99~97%.Other processes were also reviewed and factorswhich may affect the reaction selectivity were discussed.
【关键词】 ω-溴代醇-1;
α,ω-烷二醇;
氢溴酸;
溴化反应;
【Key words】 ω-bromoalkanol; α,ω-alkanediol; hydrobromic acid; bromination reaction;
【Key words】 ω-bromoalkanol; α,ω-alkanediol; hydrobromic acid; bromination reaction;
- 【文献出处】 有机化学 ,Chinese Journal of Organic cHEMISTRY , 编辑部邮箱 ,1988年03期
- 【被引频次】17
- 【下载频次】253