【摘要】 本文观察58例肝占位性病变的色氨酸耐最(ITT)试验变化,发现16例原发性肝癌ITT 均异常,F>7μol/L,而F/T<0.14占81.2%(13/16),与肝炎后肝硬化结果相近。肝血管瘤25例、肝囊肿14例、继发性肝癌3例中,仅部分以往有肝炎史者异常(7/25,3/14,2/3),但无一例F/T>0.14。此系原发性肝癌的发生常与肝硬化有关。本文结果提示ITT 试验F/T>0.14时,可做为原发性肝癌、特别是AFP 阴性者与肝血管瘤鉴别诊断的辅助指标。更多还原

【Abstract】 Intravenous tryptophan tolerance test was developed and performed in 58 cases withhepatic space-occupying lesions.16 patients with primary hepatocellular carcinoma were allpositive for the tcst,F_45′>7μmol/1 （16/16）,F/T>0.14（13/16）.The Latter was similar to thatof patients with cirrhosis.Most of the patients with hepatic hemangioma,cysts,metastaticneoplasms were negative for the test,and only a few of them having history of hepatitismight be positive （7/25,3/14,2/3）,but none of them showed F/T>0.14,because primaryhepatic carcinoma usually arises on the basis of a cirrhotic liver.Furthermore,the testmight be helpful in the differential diagnosis of hepatic tumors,especially for those primaryhepatic carcinoma patients with negative AFP to be differentiated from hepatic hemangioma.更多还原