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二羧乙基锗三氧化物对实验性冠状动脉粥样硬化的影响的病理学观察

Pathological Observation of Effects of an Organic Germanium Compound on Experimental Coronary Atherosclerosis

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【作者】 曹东铉; 金在洙; 金钟杰; 金艺兰; 金昌范;

【Author】 Cao Dongxuan (Department of Pathology)

【机构】 延边医学院病理解剖学教研室; 延边医学院病理解剖学教研室;

【摘要】 把日本大耳白兔20只分成两组,对照组10只,每天每只喂基础饲料和胆固醇0.5g,有机锗组10只,每天每只喂基础饲料,胆固醇0.5g和有机锗80mg/kg体重。经过126d喂饲之后,全部动物以空气栓塞致死。两组用HE、油红O染色、Pollak染色、von-Kossa染色。比较冠状动脉粥样硬化病变程度,结果,有机锗组与对照组病变无显著性差异。

【Abstract】 In order to observe the pathological effects of an organic germanium compound on experimental coronary atherosclerosis, 20 ,Japanese white rabbits were dividid into two groups. Each group has 10 rabbits. The group 1 were fed with 0.5g cholesterol daily. The group 2 were fed with 0.5g cholesterol as well as 80mg/kg organic germaniun compound daily. After 126 days of feeding, two group rabbits were put to death by air embolism. HE, oil red O, Pollakis and von-Kossa stains were done to each group rabbits , coronary artery. The result indicates that there is no significant difference between two groups.

【关键词】 有机锗; 冠状动脉粥样硬化; 兔; 病理学;
【Key words】 germanium; coronary atherosclerosis; rabbit; pathology;
  • 【文献出处】 延边医学院学报 ,Journal of Medical Science Yanbian University , 编辑部邮箱 ,1988年04期
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