【摘要】 白芍总甙(TGPs 40或80mg/kg·d^-1×3d,ip)可明显对抗四氯化碳（ig or sc）引起的小鼠血浆或血清谷丙转氨酶和血浆乳酸脱氢酶升高,但对谷草转氨酶的升高无明显影响。TGPs(40mg/kg·d^-1×3d,ip)对四氯化碳所致的肝病理组织改变有一定保护作用。提示TGPs可能具有保肝作用。更多还原

【Abstract】 The protective effect of TGPs on acute liver damage induced by carbon tetrachloride ( CCl4 ) was investigated in mice . TGPs ( 40 or 80mg/kg·d × 3d, ip ) reduced the elevation of plasma or serume gl- utamic pyruvic transaminase ( GPT ) and plasma lactate dehydroge-nase ( LDH ) in CCl4-intoxicated mice, but if had no significant influence on the elevation of plasma glutamic oxalacetic transaminase ( GOT).TGPs (40mg/kg·d × 3d, ip ) showed a protective effect on the histopathologic changes of liver injury induced by CCl4. The results suggest that TGPs may a protect against hepatic damage.更多还原