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白炭黑粉尘对肺脏的作用

Effect of precipitable silica dusts on lung rats.

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【摘要】 大鼠气管注入(剂量50mg)或自然吸入白炭黑粉尘,引起肺组织以细胞性结节为主的病理改变。注入组的肺重、肺胶原蛋白及类脂的含量均显著地高于正常对照组,但比石英对照组低得多。说明白炭黑粉尘对肺脏的作用表现为非特异性反应性改变。应重视它的远期作用,做好白炭黑生产和使用部门的劳动保护工作。

【Abstract】 Rats were exposed to prcipitable silica dusts by intratracheal instillation or by spontaneous inhalation. Pulmonary cellular nodularleisons were shown in both cases. The wetweight, collagen and lipid content of the lungs appeared to be significantly higher in the treated group than that in the control group, but lower than that in the quartz treated group, It indicated that the effect of precipitable silica on rat lung was a non-specific one. Attention should be paid to the long-term effect of precipitable silica and the labor protection works should be improved during its manufacture and utilization.

【关键词】 白炭黑气管注入吸入
【Key words】 silica-gel fillerlungintratracheal imstillationinhaled
  • 【被引频次】3
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