【摘要】 人工感染钩端螺旋体病猪和天然钩端螺旋体病猪的主重临床症状是体温升高、食欲减退或不吃、精神不振、困倦喜卧、消瘦、贫血、尿黄、便结和腹泻等。解剖的主要病变为各脏器贫血、出血、心肌柔软、心冠脂肪黄色。胆囊增大,内贮黄绿色或橙黄色胆汁。部分病猪的肾脏表面出现条状或点状的灰白病灶。采尿直接涂片检查钩端螺旋体,排菌最早的为15天,至75天仍有排菌。在42～75天间,陆续扑杀病猪,取肾组织作纯菌分离培养时,人工感染猪和天然病猪的肾组织均培养出钩端螺旋体。更多还原

【Abstract】 The major clinic symptoms of the experimentally and naturally infected pigs by Leptospirosis are as follows: high fever, lack of appetite or rejecting food, spiritless, anemia, emaciation, weakness and debility, lethargy and disinclination for movement, excreting yellowish urine and hard faeces, diarrhoea and etc. The histological changes in pathologic anatomy mainly appeared viscero-anemia, heamorrhages, myocardial softeness, the adipose tissue of cardiocorona showed yellow colour, the gall bladder often enlarged with greenish-brown or orange bile in it. The surface of the kidney in some infected pigs showed stripe or spot grey focus. In order to find the pathogen,a smearing examination by microscopy for urine was adapted. The leptospira were excreted earliest after 15 days of inonlation and conlinuded until to 75 days. The kidney tissue had been inoculated on the rabbit sera Korthorf’s media for pure isolation culture of leptospira, it was founded either the exprimentally or the naturally infected pigs.更多还原