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食管癌、胃癌患者血清铜、锌水平及铜/锌比值

Serum Cu & Zn Contents in Patients Suffering from Cancer of Esophagus or Stomach

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【作者】 刘菊年; 周英朋; 闵娟; 郭新宁; 吕新才;

【Author】 Liu Junian, Zhou Yingpeng, Min Juan(Dept.of Oncol., Affilated Hosp., Ningxia Med. Coll.) Gvo Xinning, LXincai(Dept. of Intern. Med., Ningxia Med. Coll.)

【机构】 宁夏医学院附属医院肿瘤科; 宁夏医学院附属医院肿瘤科; 宁夏医学院内科学教研室;

【摘要】 对61例银川市健康成人以及30例胃良性疾患患者、17例食管癌者患和43例胃癌患者(均经胃镜或手术后病理组织学证实),应用火焰原子吸收光谱法测定其血清铜、锌含量,求得银川地区健康人群血清铜、锌含量及铜/锌比值正常值范围。食管癌及胃癌患者平均铜/锌比值均增高(分别为1.77±0.81和1.52±0.49),与胃良性疾患组比较均有非常显著差异(P<0.01)。作者等建议.在胃良性疾患的监视中,一旦患者的铜/锌比值超出1.38,应高度警惕恶性肿瘤的可能性。

【Abstract】 The scrum Cu and Zn contents of altogether 151 subjects, mostly residents of Yinchuan Municipality, were assayed via flame atomic absorption spect rophotometry. They comprised 61 healthy adults and 90 esophageal/gastric disease patients (esophageal cancer 17, stomach cancer 43, diseases of storrach of benign nature 30, all diagnosed histopa thological1y following gastrofiberscope or operation). Mean serum Cu, Zn and Cu/Zn ratio were as follows respectively: 1) healthy adults 1.06±0.15ppm, 1.12±0.12ppm and 0.96±0.20; 2) patients suffering from esophageal cancer 1.49±0.23pprr, 0.94±0.24ppm and 1.77±0.81; 3) patients suffering frem itenh carcer 1.43±0.17ppm, 1.00±0.22ppm and 1.52±0.49; 4) paterts sufferirg from various types of benign stomach diseases 1.16± 0.02 ppn, 1.12±0.11ppm and 1.05± 0.2, indicating that the serum Cu/Zn retics of 2) ard 3) were both very remarkably higher than that of 4 ) (P<0.(1). The atlrs rccon nend that, during monitoring of 4), whenever the serum Cu/Zn ratio exceeds 1.33, high pti sl taken aganst the possibility of danger of malignancy.

  • 【文献出处】 宁夏医学院学报 ,Journal of Ningxia Medical College , 编辑部邮箱 ,1988年04期
  • 【被引频次】1
  • 【下载频次】19
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