【摘要】 我们在西安地区对1384人进行了HBV感染情况的血清流行病学基线研究。结果表明托儿所儿童的抗-HBs阳性率和HBV总感染率(至少在可检测的HBV指标方面)显著低于学龄儿童和成人。8岁以上儿童上述两个率与成人水平很接近。据此我们提出以下原则供在我国进行乙肝疫苗接种决策时参考:(1)在婴幼儿中应尽早普种乙肝疫苗;(2)对3岁以下儿童可考虑推广不做筛选即进行接种的方案。至于3岁以上儿童的按种方案以及学龄儿童是否有必要进行接种的问题,应该进一步加以研究。本研究还为仅用一项或二项HBV感染的血清学指标来做接种前大规模人群筛查的可能性提供了依据。更多还原

【Abstract】 A baseline seroepidemiologic study of HBV infection was conducted in 1384 people in Xi’an, The results show that in kindergarten children the prevalence rates of anti-Hbs and seropositivity (at least one of HBV markers detectable) are significantly lower than those in school children and adults. In children above 8 years of age both rates mentioned above are very close to those of adults. To conclude these, we put forward the following points for the decision making of hepatitis B vaccination in our country: (1) Hepatitis B vaccine should be given as soon as possible to all infants or newborns. (2) In children under 3 years of age, a no screening vaccination program should be extended. As to what the vaccination program for children above 3 years of age should be and whether a hepetitis B vaccination should be done or not in school children, further studies are to be carried out. The study also provides bases for the feasibility of using one or two HBV serologic markers in large scale population screening before vaccination.更多还原