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核听诊器检测进行性肌营养不良症患者心室功能的估价
Assessment of Ventricular Performance in Progressive Muscular Dystrophy by Nuclear Stethoscope
【摘要】 本文报告利用核听诊器测定33例进行性肌营养不良症(Progresive Muscular Dystrophy,简称PMD)的左心室功能,并与24佣正常人进行比较。方法:给病人弹丸式注射放射性核素(99mTc或113mIn)后,采用首次通过法和平衡法,由计算机自动分析,获得射血分数(EF)、心排出量比值(COR)、相对心排出量(RCO)、心率(HR),每博量(SV),舒张期末容积(EDV)、充盈率(FR)、射血率(ER)、高峰充盈率(PFR)参数。结果表明,在心室功能测定的9项参数中,7项指标(EF、COR、RCO、HR、SV、ER、PFR)明显低于正常值,差异有显著性意义(P<0.01),2项指标低于正常值,但无显著性意义。本方法对估计PMD的心室功能受损情况、早期诊断和观察治疗后疾病的动态变化,有一定价值。
【Abstract】 Left ventricular performance or 33 patients with Progressive Muscular Dystrophy was assessed by nuclear stethoscope,with 24 normal persons serving as controls. 9 parameters were obtained from computer autcanalysis (EF. COR, RCQ, HR, SV, EDV, FR, ER, PFR) after bolus in ection of radionuclide (99m-Tc or 110mIn), using the method of first pass and equilibrium, of 9 parameters, 7 showed significantly lower than normal value (P<0.01), while 2 gave a lower than normal value but without statistically significant differeuce. Data obtained by this method are valuable in evaluating the impairment of cardiac performance in Progressive Muscular Dystrophy, in early diagnosis and in obscrving the dynamic changes of the disease after treatment.
【Key words】 nuclear stethoscope; 99mTc; parameter; bolus in ection;
- 【文献出处】 同济医科大学学报 ,Journal of Tongji Medical University , 编辑部邮箱 ,1988年06期
- 【被引频次】1
- 【下载频次】11