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尿石形成的尿危险因素分析

Urinary Risk Factors in Calcium Stone Formation

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【作者】 刘继红; 章咏裳; 胡仁昭; 肖惠珍;

【Author】 Liu Jihong, Zhang Yongshang, Hu Renzhao, Xiao Huizhon. Research Laboratory of Urology, Tongji Hospital, Tongji Medical University, Wuhan

【机构】 同济医科大学附属同济医院泌尿外科研究室; 同济医科大学附属同济医院泌尿外科研究室;

【摘要】 本实验证实含钙尿石形成的尿危险因素是24小时尿高pH、钙、尿酸、草酸和低镁、钠/肌酐、渗透压/肌酐。本组测定值不宜计算形成结石的相对概率,宜采用判别分析。判别值为—22.620,正常人符合率为100.00%,病人为80.56%,两者判别能力有极显著性意义。其中钙、尿酸和草酸对尿石形成的贡献率较高,因此,尿石防治的重点应控制这3个因素。此外还讨论了各危险因素的作用机制及用雷达图形象地表示尿石形成的危险因素。

【Abstract】 This study shows that an increase in the urinary pH, excretion of calcium, oxalate and uric acid, and a decrease in urinary excretion of magnesium, sodium/creatinine and osmolarity/creatinine are the risk factors of calcium stone formation.It is unsuitable to calculate the overall relative probability of forming stones(PSF), but it is suitable to use discriminant analysis. The. diiicriminant score is -22.620. the correct rate of discrimination for normal subjects and stone patients is 100.00 and 80.56% respectively. The discriminant analysis is highly significant. Since the contributive rates of calcium, oxalate and uric acid are higher in stone formation, the prevention of stone formation lies mainly in controling these factors. The radargraphs express imaginally the risk factors in oxalate, phosphate and urate stone patients. The mechanism of eacb risk factor was also discussed.

【关键词】 尿结石; 钙; 草酸盐; 尿酸; 镁;
【Key words】 urinary calculi; calcium; oxalates; uric acid; magnesium;
【基金】 国家自然科学基金
  • 【文献出处】 同济医科大学学报 ,Journal of Tongji Medical University , 编辑部邮箱 ,1988年05期
  • 【被引频次】8
  • 【下载频次】37
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