【摘要】 本文观察了15只雌性家兔服用复方十八甲后血脂指标的变化（OC 组）。另15只家兔服可溶性淀粉赋形剂作为对照组。实验家兔每四周给药一次,2片/只,于每服药周期的中、末期（即每周期的第2周和第4周）取空腹血测定血清脂质含量变化。连继观察28周,结果发现服用复方十八甲家兔的血清HDL-C、HDL₂-C 水平、HDL₂-C/HDL₃-C 及HDL-C/TCh 比值均明显高于对照组（P<0.05）;而TCh、LDL-C 及致动脉粥样硬化指数等值明显低于对照组（P<0.05）。结果提示复方十八甲对家兔脂代谢产生良好影响。更多还原

【Abstract】 15 female adult rabbits feeding on combined 18 dl-norgestrel were used as the oralcontraceptive group（OC group）,and another 15 were control group.Every rabbit ofthe OC group was given two pills every 4 weeks as a cycle,while the rabbits of the controlgroup were given placebo.Fast serum was taken at the middle and the end of thecycle to determine the changes of the lipid contents for 28 weeks.As a result,we found thatthe levels of serum high-density lipoprotein cholesterol（HDL-C）,HDL₂-C,HDL-C/TCH,and HDL₂-C/HDL₃-C ratios were significantly higher in OC group than those in thecontrol group（P<0.05）,whereas TCH,TG,LDL-C and ASI levels were significantly lowerin OC group（P>0.05）.The results suggest that the pills have a good effect on lipid andlipoprotein metabolism in rabbits.更多还原