【摘要】 本文用SEM分析研究生物活性玻璃陶瓷植入动物软硬组织后种植界面的徽观状态,并比较其它三种植入材料与骨的结合形式。结果认为:（1）生物活性玻璃陶瓷种植三个月后,界面可形成骨性结合。在材料微孔内可见胶原纤维长入和钙盐结晶沉积形成的骨样结构。新骨表面成骨细胞活跃。（2）TC₄钛合金,单晶、多晶氧化铝陶瓷分别经45天到300天的分期观察,界面形成软结合,未见成骨细胞活跃。（3）生物活性玻璃陶瓷在骨环境中有诱导骨生长的能力,这种能力可能是骨界面微电化学反应的结果,而在肌组织中则不具有这种诱导作用。（4）生物活性玻璃陶瓷与肌组织接触147天也不会由于粗糙的表面产生组织的炎症反应,而形成50μ—130μ厚致密的纤维囊包裹,保护肌肉活动时不受种植体机械的刺激。更多还原

【Abstract】 The microstate of the Interface after bioactive glass ceramic being implanted into the soft and the hard tissues of animal was studied. The bond types of three implanting materials in the bone were also compared. The results showed: 1. Osseointegration could bef ormed on the interface after the bioactive glass ceramic was implanted in three months. Bone-like structure was formed by the introducing of collagen fiber and the depositing of calcium salt crystal. Osteoblasts were active on the surface of new bone formed. 2. The interface was formed soft bond without osteoblast active by the stage observations from 45 days to 300 days respectively with TC4 titanium alloy, monocrystal and polycrystal aluminum oxide ceramic. 3. Bioactive glass ceramic possessed the ability of inducing bone growth in the bone enviroment, which was probably the result by the microelectric chemical reaction on the bone interface. The inducing effect didn’t exist in the muscle tissue. 4. The ceramic with rough surface didn’t produce The tissue inflammation reaction until it contacted with the muscle tissue in 147 days, but did form the thick fiber capsule wrapping with 50-130um, which protected soft tissuc from mechanical irratation of the implant when the muselg acted.更多还原