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131I-CEA M cAb免疫显像诊断卵巢癌的初步研究
A PRELIMINARY STUDY OF RADIOIMMUNOIMAGING OF OVARIAN MALIGNANCY WITH I-131 LABELLED CEA MONOCLONAL ANTIBODY
【摘要】 用131I-CEA McAb放射免疫显像诊断10例卵巢癌患者,使用γ-闪烁显像辅以微机图像处理技术和双核素减影术获得较好效果。10例全部阳性显像,与手术及病理结果完全相符,卵巢癌RII分期与手术分期亦完全符合。31处转移灶发现30处,阳性率97%,最小检出病灶直径1.5cm。本法在对病灶进行定性诊断同时可直接显示病灶位置、形态、大小及数量。对早期发现、指导临床分期、估计预后有较高的临床价值。
【Abstract】 Ten cases of ovarian cancers have been detected with I 131 labelled CEA McAb and computer assisted clual radionuclide subtraction tech-nique.The lesions(both primary and secondary)are clearly visualized andproved by surgical and pathohistological findings.30 of 31 metastatic lesionsare localized with a positive rate 97%.It seems to be a sensitive andspecific procedure for early diagnosis of ovarian cancer so far.It is alsovaluable for staging clinical course and making decision on treatment,assessing the prognosis of ovarian cancer as well.
【Key words】 Ovarian neoplasms; Radioimmunoimaging; Antibodies,monoclonal; Carcinoembry onic antigen;
- 【文献出处】 山东医科大学学报 , 编辑部邮箱 ,1988年04期
- 【被引频次】5
- 【下载频次】8