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动脉粥样硬化发病机制中神经系统作用的研究

The Investigation of the Effect of Nervous System in the Pathogenesis of Atherosclerosis

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【作者】 姚君慎; 王家富; 李宏英; 刘同美; 吴强; 段文卓; 姜波; 王中伟;

【Author】 Yao Junshen, (Departmerit of Pathophysiology)

【机构】 淮坊医学院病理生理学教研室; 淮坊医学院病理生理学教研室; 淮坊医学院心血管药理研究室;

【摘要】 本研究采用一侧颈总动脉中段原位自体移植的新方法,旨在制备研究神经系统在动粥发病机制中作用的动物模型。通过二批试验,观察到自体移植段无任何粥样病变,相反,对照的无损伤颈总动脉有明显的动脉粥样硬化斑块。实验结果充分证明,神经系统在动粥的发病机制中起着重要作用,此结果可作为神经系统在动粥的发病机制中起作用的直接证据。

【Abstract】 The new method of one Lateral carotid artery original location autograft is used in present paper. This purpose which is to prepare an animal model is to study the effect of nervous system in the pathoge- nesis of atherosclerosis. In two experiments we observe that atherosclero- tic lesions have been not shown within the segment of carotid artery autograft. Contray, control intact carotid arteries have apparently atherosclerotic plaques. Experimental results clearly indicate that the nervous system in the pathogenesis of atherosclerosis plays an important role. This results were made as a direct evidence of the effect of nervous system in the pathogensis of atherosclerosis.

  • 【文献出处】 潍坊医学院学报 ,Acta Academiae Medicinae Weifang , 编辑部邮箱 ,1988年01期
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