【摘要】 硬膜外麻醉致收缩压降低25％时,静滴多巴酚丁胺或麻黄素,使血压回升至术前水平,比较低血压治疗前后的血流动力学改变。舒张压和平均动脉压均下降,心排出量、心输出量和心指数减少,而心率、外周血管阻力代偿性增加,微循环半更新时间延长。静滴多巴酚丁胺或麻黄素均可使血压升高,但麻黄素升压速度比多巴酚丁胺慢1倍,且增加心率和外周阻力。对心功能不全或心脑血流灌注处于临界水平的病人可能有害。麻黄素这一特点可能与兴奋α、β-受体,促进去甲肾上腺素释放有关。更多还原

【Abstract】 SBP, DBP, MAP, SV, CO and CI were decreased by Epidural anethesia in the operation of upper abdomen and HR and TPR increased compensatively and ALT prolonged. Ephedrine or Dobutamine was used to treat hypotension in 10 cases The onset of BP raising after Ephedrine was slower than that after Dobutamine. Increase in BP and TPR by ephedrine may be harmful to the patients with heart failure or with lower blood flow in critical level of heart or brain.更多还原