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丙硫咪唑治疗儿童蛲虫病80例效果观察

Clinical efficacy of Albendazole in the treatment of 80 cases of enterobiasis in children

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【作者】 齐宗春; 张文玉; 朱丽贤; 张艳芳;

【Author】 Qi Zhongchun

【机构】 佳木斯医学院寄生虫学教研室; 佳木斯医学院寄生虫学教研室;

【摘要】 <正> 丙硫咪唑(Albendazole)是一种新型抗蠕虫药物,对吸虫、绦虫、线虫均有杀灭作用。自Rossignol提出治疗蛲虫以来,开始将丙硫咪唑试用于蛲虫病。我们于1987~1988年试用该药治疗儿童蛲虫病,报道结果如下。 1 对象和方法:采用透明胶纸法对两所幼儿园300余名儿童进行检查,每日午后连续3d于儿童午睡后进行。发现虫卵为阳性,三次均未发现虫卵为阴性。阳性者给予丙硫咪唑治疗。药物:丙硫咪唑,胶囊,每粒含主药100mg,杭州药厂出品,批号850701。治疗分组:2~4岁儿童46例按100mg,5~7岁儿童34例按200mg,一次顿服。由幼儿园保育员和保健医生亲自完成。治疗期间及治疗结束后随时观察药物的副作

【Abstract】 This paper reports 80 cases of enterobiasis in children treated with Albendazole. 46 cases of 2~4 years old were treated with 100 mg of Albendazole, with 100% of the cure rate. 34 cases of 5~7 years old were treated with 200 mg of Altendazole, with 100% of cure rate. Eggs observed by microscope showed deformation and even became black, and dying indicrting that Albendazole has a better effect on killing pinworm and eggs of E. rermicularis.

【关键词】 丙硫咪唑; 近期治愈率; 蛲虫病; 儿童;
【Key words】 Albendazole; enteobiasis; recent period cure rate;
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