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长时间TPN支持病人的钙平衡与静脉维生素D的应用
Calcium Balance and the Dosage of i.v.Vit.D Supplement in Long-term Total Parenteral Nutrition Support Patient
【摘要】 在感染/创伤病人行长时间TPN支持时,钙平衡与维生素D需要量的研究国内尚乏报道。1985~1986年间作者对2例长时间TPN支持病人及6例手术后TPN支持病人比较了钙平衡与静脉补充维生素D量的关系。 研究结果提示,在TPN支持下,每天经静脉补充维生素D200国际单位,可以使尿钙排出显著降低,有助于维持正常血钙及正钙平衡。但是每天经静脉补充维生素D1000国际单位,则可导致尿钙排出增加,呈现较深的负钙平衡。 作者认为,经静脉补充大剂量维生素D,,有直接导致骨代谢障碍的可能。
【Abstract】 Calcium metabolism and i.v. vitamin D supplement were not well understood during long-term TPN support in Chinese patientA perspective randomized study was performed in surgical metabolism research ward around 1985-1986. There wese 6 patients enrolled as the effect of vitamin D in calcium balance, other 2 long-term TPN support patients were studied for dosage and calcium balance.The results show that; daily supplement of 200 IU of vitamin D can keep the satisfactory calcium balance,but the dosage increasing to 1000 IU per day will result the increasing of calcium excretion.
【Key words】 Total parenteral nutrition ( TPN ) Cilcium balance Yitamin D Expense of bone calcium;
- 【文献出处】 生理科学 , 编辑部邮箱 ,1988年06期
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