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电刺激尾核头部对丘脑后核痛相关神经元电活动的影响

Influence of Stimulating Caudate Nucleus on the Discharges of the Pain-related Neurons in the Posterior Nucleus of Thalamus (PO)

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【作者】 赵维华刘敏芝

【Author】 Zhao Weihua and Liu Minzhi(Department of Physiology, Bethune University of Medical Science, Changchun)

【机构】 白求恩医科大学生理教研室白求恩医科大学生理教研室 长春长春

【摘要】 在61只大鼠的丘脑后核(PO)记录到了516个神经元,其中44.19%是痛相关神经元。它们的痛反应能被吗排类物药所抑制。电刺激尾核头部对痛相关神经元主要产生抑制作用。本文就以上结果在痛觉生理和镇痛中的意义进行了讨论。

【Abstract】 Experiments were performed on 61 rats immobilized with gallamine trie-thiodide. 516 units in PO were extracellularly recorded and 44.19% of them were pain-related neurons.Their pain reaction could be blocked by morphine and fentanyl. stimulating caudate nucleus mainly produced the inhibitory effects on the pain-related neurons. The meaning of the results in analgesia and pain physiology was discussed.

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