节点文献
国产乙型肝炎疫苗和HBIG联合阻断乙型肝炎母婴传播效果研究
Prevention of Perinatal Transmission of Hepatitis B Virus to Infants of HBsAg-Positive HBV Carrier Mothers by Hepatitis B Immune Globulin and HBV Vaccine
【摘要】 本文采用乙型肝炎疫苗和HBIG,经3种不同的联合免疫方案,对阻断乙型肝炎母婴传播的效果进行了研究。结果证明,3个组联合免疫后12个月的抗-HBs阳转率为75%~90%;抗-HBs平均浓度(mIU/ml)为32.55~42.93;阻断率为80.00%~93.3%。联合免疫的效果是满意的。
【Abstract】 The efficacy of hepatitis B immune globulin(HBIG) combined with hepatitis B virus vaccine in preventing vertical transmission of HBV were investigated on 45 infants born to HBsAg-positive HBV carrier mothers. The infants were divided randomly into 3 groups with different scheme of application. It was found that the earlier the infant received HBV vaccine, the higher the anti-HBs appeared in his(her)blood and the better the effect of prevention was. The infants displaying HBsAg in their blood at birth were not effectively protected by HBIG and HBV vaccine.
- 【文献出处】 哈尔滨医科大学学报 ,Journal of Harbin Medical University , 编辑部邮箱 ,1988年05期
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