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硒、锰对大鼠心肌辅酶Q含量的影响

The Effect of Selenium and Manganese on Content of Ubiquinone in Myocardium of Rats

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【作者】 张殿清; 刘立竹; 曾绍娟; 杨洪昌;

【Author】 Zhang Dianqing(Institute of Keshan Disease)

【机构】 哈尔滨医科大学克山病研究所; 哈师专; 哈尔滨医科大学克山病研究所 进修教师;

【摘要】 本文叙述了硒、錳对大鼠心肌辅酶Q代谢的影响,结果发现注錳组大鼠心肌辅酶Q含量明显低于口服组。冰泳组也比未冰泳组低,说明过量錳能引起心肌损伤,冰泳能加重其作用。

【Abstract】 The effect of selenium and manganese on metabolism of ubiquinone in mycardium of rats are reported. The results showed that the contents of ubiquinone-8 in myocardium of rats injected manganese group were lower than that of oral groups and their difference is significant(P<0.05). The contents of ubiquinone-9 in injected manganese group were 26.1% and 25.2% respectively lower than that of normal selenium and manganese group and normal selenium and high manganese group. The contents of ubiquinone-8 in myocardium of rats in iceswim group were also lower than that of no ice-swim group. The result showed that the excess of manganese could result in the damage of the myocardium and ice-swim made this damage more serious.

【关键词】 硒; 锰; 辅酶Q; 心肌损伤;
【Key words】 Selenium; Manganese; Ubiquinone; Damage; Myocardium;
【基金】 国家七五攻关课题
  • 【文献出处】 哈尔滨医科大学学报 ,Journal of Harbin Medical University , 编辑部邮箱 ,1988年04期
  • 【被引频次】1
  • 【下载频次】34
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