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99mTc-葡聚糖乳内淋巴显像及其临床评价

CLINICAL EVALUATION OF 99mTc-DEXTRAN INTERNAL MAMMARY LYMPHOSCINTIGRAPHY

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【作者】 管昌田; 谭天秩; 邓候富; 陈佩珍;

【Author】 Guan Changtian;Tan Tianzhi;Deng Houfu Department of Nuclear Medicine Chen Peizhen Department of Surgery

【机构】 华西医大核医学教研室; 华西医大外科学教研室;

【摘要】 本文报告26例正常人和35例乳腺包块99mTc-葡聚糖乳内淋巴显像的结果。正常人绝大多数双侧淋巴结数和(或)显影浓淡不对称,并发现左右交叉引流和先天性单链各2例;乳癌乳内淋巴转移者双侧或单侧淋巴链不显影,或一侧淋巴链仅低位淋巴结显影而高位缺如。本法判断淋巴受累的灵敏度为100%,特异性为85.2%,准确性为88.6%,假阳性为14.8%,假阴性为零。

【Abstract】 99mTc-dextran internal mammary lym-phoscintigraphy (IML) was performed in26 nosmal control subjects and 35 cases ofbre ast mass. In the 26 normal control subjects,cross drainage between parasternal lymphat-ics and an unilateral chain of parasternalnodes were observed in two cases each; bilat-eral parasternal node chain was seen in theremaining cases, but the number, size andintensity of radioactivity uptake of the par-asternal nodes were asymmetric bilaterallyin most of the cases. Abnormal patterns ofIML in the patients with internal mammarynode metastasis included nonvisualized bilat-eral or unilateral lymphnode chain and vis-ualized ipsilateral diaphragmatic node withcompletely visualized contralateral lymphnodechain. In predicting neoplastic: involvementof internal mammary lymphnodes. sensitivity,specificity, accuracy, false positive and falsenegative of IML were 100%, 85.2%, 88.6%,14.8% and 0%, respectively.

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