【摘要】 作者利用离子色谱仪对12名青少年的龈上集合菌斑细胞外液有机酸在漱糖前后的种类和含量以及非刺激性唾液有机酸的种类和含量进行了测定。结果表明:在休息状态时,菌斑细胞外液中有机酸含量明显地高于非刺激性唾液中的含量;无论漱糖前后,菌斑细胞外液中高pKa酸(乙、丙酸)的浓度都高于低pKa酸(乳、甲酸)的浓度;漱糖后,菌斑细胞外液中高、低pKa酸的时间依赖性变化与其pH的变化存在相互关系。漱糖后30～35分钟时,龋活跃组与无龋组间,乳酸浓度变化的差异无显著性(P>0.05)。任何时候,菌斑细胞外液中的乙酸浓度都高。提示乙酸与龋损过程之间,可能存在一定关系,值得进一步研究。更多还原

【Abstract】 The organic acids in unstimulatedsaliva and the extracellular fluids of dentalplaques from 12 middle school studentswere measured by means of ion-chromato-graphy. The acids in the plaques wereanalysed before and 5-10, 30-35, 60-65 minafter rinsing with 10% sucrose solution. Asignificant difference of the acids betweenthe extracellular fluids of resting plaquesand unstimulated saliva was found. In theextracellular fluids of plaques the totalamounts of high pKa acids (i. e. aceticand propanoic acids) were higher than thoseof low pKa acids (i.e., lactic and formicacids) before and after the sucrose rinse.A relationship of the time-dependentchanges between the ratio of low pKa tohigh pKa acids and pH was observed in theextracellular fluids of plaques after the su-crose rinse.No significant difference in lacticacid concentration between the caries-activeand caries-free subjects 30-35 min afterthe sugar rinse was found. The amountof acetic acid was much higher in theextracellular fluids of the dental plaque atany time. It is suggested that there maybe some relationship between acetic acidand caries process.更多还原