【摘要】 作者对21例行瓣膜置换的患者,进行了术前至术后48小时的血流动力学研究。术后肺动脉平均压、在房平均压及体循环阻力明显降低,心指数和每搏指数显著增加,其中10例外径为29mm和31mm的牦牛心包瓣膜:跨瓣压差分别为4.7和6.3mmHg;瓣口面积(8例)分别为1.7和2.0cm~2。病变的二尖瓣用牦牛心包瓣膜置换后,术后近期的血流动力学有明显改善。更多还原

【Abstract】 Perioperative hemodynamic changesfollowing mitral valve replacement usingyak pericardial xenograft were measured in21 patients with acquired mitral valve dis-ease from May, 1985 to June, 1986. Preoperatively, a state of compensatorycardiac failure was suggested by the follow-ing:an increased heart rate;low cardiac andstroke volume index;and increased systemicvascular resistance. Both the mean pulmo-nary artery and left atrial pressures wereelevated as well. Immediate hemodynamicimprovement followed the valve replace-ment.The reducing of pulmonary arterypressure,left atrial pressure, systemic vascu-lar resistance and the increasing of cardiacindex, stroke volume index were observed.Among ten out of 21 cases, the mean mitralvalve gradients and the mean effective ori-fice areas for valves with 29 and 31 mm inexternal diameters were 4.7 and 6.3 mmHg,and 1.7 and 2.0 cm~2 respectively. It is thus concluded that hemodynamicsis improved immediately after the mitralvalve replacement with yak pericardialxenograft.However,further observation isneeded for long-term evaluation.更多还原