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骨肉瘤的超微结构研究

AN ULTRASTRUCTURAL STUDY OF STEOSARCOMA

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【作者】 黄跃; 杨光华; 谭永淑; 王远萍;

【Author】 Huang Yue;Yang Guanghua;Tan Yongshu Department of Pathology Wang Yuanping Electron Microscope Laboratory

【机构】 华西医科大学病理学教研室; 华西医科大学电子显微镜室;

【摘要】 作者在电镜下,观察了42例各型骨肉瘤组织中含多种瘤细胞成份,根据类型的不同,瘤细胞成份和其所产生的间质有所差异。

【Abstract】 Forty-two osteosarcomas of varioustypes were studied ultrastructurally. It wasfound that osteosarcomas of differenttypes were composed of a variety of tumorcells, including osteoblasts, chondroblasts,fibroblasts,histiocytes, multinucleated giantcells, myofibroblasts and primitive mesen-chymal cells as well as its respective matrix,and one of them might be dominant.Thesefindings give a strong backing for thepresent histologic classification of osteosar-coma. Some specific structures were foundin the tumor cells, such as single cilia,branched cylindrical structures and intra-cytoplasmic lumen-like structure, whichhave not been reported before.Additionally,the componant of tumors,their relationship,the mode of forming neoplastic osteoidmatrix, and the histogenesis of osteosarco-mas are discussed in detail.

【关键词】 骨肉瘤; 超微结构; 瘤细胞; 间质;
【Key words】 Osteosarcoma; Ultrastructure; Tumor cells; Matrix;
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