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抗肿瘤新药—乙双吗啉临床疗效观察

A report of the clinical curative effect of bimolane (AT—1727)

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【作者】 熊沐霖;

【Author】 Xiong Mulin Department of Oncology, the First Affiliated Hospital

【机构】 河南医科大学一附院肿瘤科;

【摘要】 本文报告单用乙双吗啉治疗89例晚期恶性肿瘤,总有效率(CR+PR+MR)为37.08%(33/89例)。特效和显效率(CR+PR)为15.73%,中位缓解期13周,对恶性淋巴瘤有较好疗效。乙双吗啉为口服胶囊剂型,化疗指数高,毒性小,有胃肠不适和轻度白细胞下降,两周多可恢复,故是一种应用安全和使用方便的抗肿瘤新药。

【Abstract】 89 patients with advanced carcinoma were treated with bimolane in our hos-pital. The remission rate was 15.73% (14/89 cases). The overall response rate was37.08%(33/89 cases). The median duration of remission was 13 weeks. IT was ra-ther effective to lymphosacoma. Bimolane can be used safely and conveniently with low toxicity and high che-motherapeutic index, and it can be administered orally. Gastrointestinal upsets andmild leukopenia are the main side effects of this drug.

【关键词】 乙双吗啉; 恶性肿瘤; 毒性反应;
【Key words】 bimolane; malignant tumour; toxic reaction;
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