【摘要】 健康人对照组,肝阳上亢、阴虚阳亢、肝肾阴虚三证型组,分别测定尿儿茶酚胺（CA）、肾上腺素（E）、去甲肾上腺素（NE）及3—甲氧—4—羟基苯乙二醇硫酸酯盐（MHPG—SO₄）含量并进行组间比较;结果发现肝阳上亢组病人尿CA、NE 含量显著高于健康人组及阴虚阳亢、肝肾阴虚组。三证散组的尿 MHPG—SO₄ 含量均显著低于健康人组,各证型组间含量均数差别无显著性。提示尿 CA,NE可考虑为肝阳上亢证的一个临床生化指标。更多还原

【Abstract】 The three symptom-complex groups (Liver Yang Rising, LYE; Yin Deficiency and Yang Excess, YDYE; Liver-Kidney Yin Deficiency, LKYD) are said to come from imbalance of Yin-Yang in classical TCM literatures. They were frequently seen in cases suffering from hypertension, hyperthyroidism, climacteric syndyome, etc. The 24h urinary CA, E, NE contents (μg), NE/E ratio and MHPG-SO4 were determined in 132 and 208 patients respectively in comparison with 30 and 34 normal subjects. The result showed that the urinary CA, NE levels were significantly increased in LYR group (45.24±10.40, 27.72 ±10.06) as compared with the control (28.40±7.07, 16.75±6.09), and YDYE group (36.84±15.38, 21.09±8.82) but LKYD group (24.90 ±8.40, 16.84±6.88) showed no significant differance, the 24h urinary MHPG-SO4 contents was significantly decreased in LYR group (1060.54±457.19), YDYE group (1104.92±441.25) and LKYD group (1218.34±358.58) as compared with the control (1401.28±266.84), but no significant differences in these three groups. It is suggested that urinary CA, NE contents may represent a useful biochemical index in symptom-complex of LYR.更多还原