【摘要】 本文对58例肝占位性病变患者作色氨酸耐量试验,结果显示16例原发性肝癌全部为明显肝功能损害:F45>7μmol/L(16/16),F/T<0.14(13/13),与肝硬化对照组相似;而肝血管瘤、肝囊肿及转移性肝癌中多为正常,少数有肝炎史者为轻度损害(7/25,3/14,2/3),无F/T>0.14者。这是因为原发性肝癌常有肝硬化的基础。提示本试验有助于肝占位病变的鉴别诊断,特别是AFP阴性的原发性肝癌。更多还原

【Abstract】 Intravenous Tryptophan Tolerance Test was developed and perfomed in 58 cases of hepatic space-occupying lesionsAll 16 patients with primary hepatocellular carcinoma(PHC)were positive: F45′>7 μmol/L(16/16), F/T>0. 14(13/16), similar to that of patients with cirrhosis. In patients with hepatic hamangioma, cysts, metastatic neoplasms, most were negative and only a few with a history of the hepatitis were wsakly positive(7/25, 2/14, 2/3), but none of them showed F/T>0. 14. It is because that the PHC usually arises on the basis of a cirrhotic liver. This study suggests that the test could be helpful in tile differential diagnosis of hepatic tumors, especially of PHC with negative AFP.更多还原