【摘要】 <正> 随着心脏外科手术的开展,心导管检查日益增多,为了解心导管检查时患者所受的辐射剂量及由此而产生的染色体畸变,对今后提出合适的防护措施和合理使用X线诊断技术提供依据,本文对17例一次心导管检查或导管合并造影时患者所受辐射剂量及染色体畸变分析作一报道,并加以讨论。更多还原

【Abstract】 The relationship between the radiation doses and the chromosomal aberrations of peripheral lymphocytes was studied in patients under-going catheterization with or without angiocardiography.The radiation doses were estimated and chromosomal aberration analyses were carried out in 17 cases. They consisted of 10 males and 7 females at the age of 4 to 26 years with an average of 14 years.Doses in the chest and gonadal regions were measured with calibrated thermolumines-cent dosimeters. Peripheral blood samples were taken immediately before and after the diagnostic procedure for chromosome analyses.Results showed that the average doses in the gonad region during cardiac catheterization with and without angiocardiography were 2.4 and 0.83 kC/kg respectively, while those in the chest region were as high as 0.93 and 0.54kC/kg respectively. The chromosome aberration rate in both groups were significantly higher (2.75-3.33%) than the control value (0.22-0.75%) which was determined before X ray examination. No statistically significant difference of chromosome aberration yield was found between the two groups with and without angiocardiography.更多还原