【摘要】 41只家兔在麻醉状态下胆流速度均匀,平均3.4毫升/公斤/时。对其中35只兔的膈下迷走神经施以电刺激,7只无反应,28只胆流有不同程度抑制。在这28只中,当膈下腹、背两侧迷走神经分别受到刺激时,都出现反应的有9只(32％);仅对刺激腹侧神经有反应的15只(53.6％);仅对刺激背侧神经有反应的4只(14.3％)。本工作揭示:支配家兔胆管活动的迷走神经并非仅仅是膈下腹侧支,而背侧支也有相当重要的作用。关于家兔胆汁分泌的研究曾有一些报道~[1.2.3];梅懋华等~[1]将家兔膈下双侧迷走神置于一个电极下,使两者同时受到刺激,绝大多数动物的胆汁流出速度发生变化.并证明这一效应的作用环节在于神经的兴奋引起胆管发生不同程度的收缩,阻碍了胆汁流出,而不是改变肝的分泌或胆囊活动.根据现有知识,家兔膈下腹侧迷走神经形成胃前神经丛,后者再发出纤维分布到肝~[4];至于膈下背侧迷走神经是否有纤维分布到肝和胆管,以及对胆汁流出是否产生影响,均未见报道,我们在实验中,注意到,若单独对家兔膈下腹侧或前侧迷走神经分别施以电刺激,各侧神经对胆汁排出能否产生影响,这在不同个体并不一致.于是导出了这样的问题;家兔膈下背侧迷走神经,是否也能借缩胆管机制影响胆汁的排出速度?如果能够,那么这两侧神经表现此种作用的场合各占多大比更多还原

【Abstract】 Basic hepatic bile flow of 41 rabbits which anesthetized with pentobarbital sodium was investigated .The bile f low (recorded droply on a kymograph) was steady and had an average volume of 3.4 ml/kg/h, concluded from an observation of total 1335 minutes. With the electrods placed respectively around the bilateral subdiaphragmatic vagus nerves, 35 of the animals were subjected to eletric stimulating ( 10v, 2ms, 8 - l6Hz for 3-5 minutes) . When there was an electric stimulating appled, 28 ( 80% ) out of the 35 animals gave alternations (mainly inhibitory responses) of bile flow while the other 7 animals (20%) remained unchanged. Among the 28 rabbits, 9 (32%) animals gave responses to stimulating on dither side of subdiaphragmatic vagus nerves, 15 (53.6%) animals to ventral and 4 (14.3%) animals to dorsal stimulating.These figures revealed that variation exists among rabbits in innervation by vagus nerves of biliary tract and the fibers supplying biliary tracts not only come from the ventral vagus nerves but also from the dorsal.更多还原