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茶叶的抗突变作用

ANTI-MUTAGENIC EFFECT OF TEA

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【作者】 阮萃才; 梁远; 刘宗河;

【Author】 Guangxi Cancer Institute Ruan Cuicai,et al

【机构】 广西肿瘤研究所; 广西肿瘤研究所;

【摘要】 应用Ames试验对绿茶和红茶进行抗诱变性研究.实验用绿茶和红茶的丙酮提取物诱导TA98和TA100突变株对2-氨基芴、黄曲霉毒素B1和迭氮钠等致突变物的回复突变,观察其抑制致突变作用.结果表明两种茶叶对几种性质不同、结构各异、致癌作用机理不同的致突变或致癌物均有显著的抗突变作用.

【Abstract】 Ames test was used in testing green tea and black tea for their anti-mutagenic effect on 2-AF, AFB1, NaN3 induced mutagenic activity.The tested tea were extracted repeatedly with acetone and were detected with strains TA98 and TA100 The revertants induced by 2-AF, AFB1, NaN3 decreased significantly when green tea and black tea were added into the medium.The results revealed that these two kinds of green and black tea had remarkable inhibitory effect on 2-AF, AFB1, NaN3 induced mutagenic activity for TA98, TA100; and also suggested that anti-mutagenic substances were present in these tea.This experiment provides a scientific basis for the study of food resources in the prevention of carcinogenesis.

【关键词】 茶叶; 突变; 抗突变; 癌的化学预防;
【Key words】 Tea; Mutation; Antimutation; Chemoprevention of Cancer;
  • 【被引频次】10
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