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实验感染乙型肝炎病毒的树鼩血清HBsAg及抗-HBs的表现类型

Expressive Patterns of HBsAg and Anti-HBs in the Sera of HBV infected Tree Shrews

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【作者】 苏建家严瑞琪甘友全周德南黄定瑞黄国华

【Author】 Guangxi Cauccr Instisute Su Jianjia, et al

【机构】 广西肿瘤防治研究所广西肿瘤防治研究所

【摘要】 57只实验树鼩接种HBV后,用分子杂交技术、电镜及肝组织免疫酶标方法检测,有39只证实已获感染.这39只动物血清HBsAg及抗-HBs(PHA)表现有6种形式,与人感染HBV后的表现形式相似.表明树鼩是可用于HBV实验感染研究的较好的动物.

【Abstract】 57 experimental tree shrews inoculated with human HBV were examinated by molecular hybridization test, electromicroscopy and immunohisto-chemistry.39 of 57 tree shrews were infected by human HBV.There were six expressive patterns of HBsAg and anti-HBs in the sera of HBV infected tree shrews by PHA.They are similar to that in the sera of HBV infected human.The results showed that tree shrew may be served as an animal model for studying HBV.

【关键词】 树鼩乙型肝炎病毒接种
【Key words】 tree shrewhepatitis B virusanimal model.
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