【摘要】 高温作为辐射增敏技术,与放疗相结合,用于临床治疗肿瘤已取得显著的进展。我们应用同位素标记的方法,对人外周血淋巴细胞进行高温处理(43℃),结果提示高温能影响淋巴细胞DNA、RNA及蛋白质的合成,其热敏感性顺序与辐射相同,即DNA>RNA>蛋白质,并就其作用机制进行了详细的讨论。更多还原

【Abstract】 Through heat-treating the human peripheral lymphocytes and with the isotope labeling method, it is concluded that as a kind of technique of enhancing radiation sensitivity, hyperthermia, in combination with radiotherapy, has made a great progress in the clinical treatment of the patients with cancer and can carry the offect on the DNA, RNA and synthesis of protein in human peripheral lymphocytes, and the heat-sensitivity sequence is the same as that of radiation, that is, DNA>RNA protein.In this paper, the principles of the effeet are discussed in some detail.更多还原